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May 07, 2015
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Experimental animal research plays a pivotal role in the development of clinical transplantation practice. The porcine orthotopic liver transplantation model (OLTx) closely resembles human conditions and is frequently used in clinically oriented research. The following protocol contains all information for a reliable porcine OLTx model using an active porto-caval-jugular shunt.
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Spetzler, V. N., Goldaracena, N., Knaak, J. M., Louis, K. S., Selzner, N., Selzner, M. Technique of Porcine Liver Procurement and Orthotopic Transplantation using an Active Porto-Caval Shunt. J. Vis. Exp. (99), e52055, doi:10.3791/52055 (2015).
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