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A Novel Light Damage Paradigm for Use in Retinal Regeneration Studies in Adult Zebrafish
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Neuroscience
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JoVE Journal Neuroscience
A Novel Light Damage Paradigm for Use in Retinal Regeneration Studies in Adult Zebrafish

A Novel Light Damage Paradigm for Use in Retinal Regeneration Studies in Adult Zebrafish

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10,062 Views

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09:31 min

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October 24, 2013

DOI:

10.3791/51017-v

DOI:
10.3791/51017-v

•

09:31 min
October 24, 2013

•

7 Views
,
1Department of Anatomy and Cell Biology,Wayne State University School of Medicine, 2Department of Opthalmology,Wayne State University School of Medicine

Summary

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Multiple light damage protocols have been described to damage photoreceptors and consequently induce a retinal regeneration response in adult zebrafish. This protocol describes an improved method that can be used in pigmented animals and that damages the vast majority of rod and cone photoreceptors across the entire retina.

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Cite this Article

Thomas, J. L., Thummel, R. A Novel Light Damage Paradigm for Use in Retinal Regeneration Studies in Adult Zebrafish. J. Vis. Exp. (80), e51017, doi:10.3791/51017 (2013).

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