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A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats
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Behavior
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JoVE Journal Behavior
A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats

A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats

English

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10,859 Views

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10:35 min

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November 11, 2013

DOI:

10.3791/50751-v

DOI:
10.3791/50751-v

•

10:35 min
November 11, 2013

•

4 Views
, ,
1Department of Psychology, Center for Studies in Behavioural Neurobiology/Groupe de Recherche en Neurobiologie Comportementale,Concordia University

Summary

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A procedure that allows a demonstration of robust augmentation of drug seeking in food-restricted rats is described. Following heroin self-administration training, rats go through an abstinence period, in a drug-free environment, during which they are mildly food restricted. Drug seeking is then tested in the drug-associated environment.

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Sedki, F., D'Cunha, T., Shalev, U. A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats. J. Vis. Exp. (81), e50751, doi:10.3791/50751 (2013).

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