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创建动态图像的短命多巴胺波动与LP-ntPET：多巴胺电影吸烟

JoVE Journal
Behavior

This content is Free Access.

JoVE Journal Behavior

Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET: Dopamine Movies of Cigarette Smoking

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创建动态图像的短命多巴胺波动与LP-ntPET：多巴胺电影吸烟

17,988 Views

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14:21 min

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August 06, 2013

DOI:

10.3791/50358-v

DOI:

10.3791/50358-v

•

14:21 min

August 06, 2013

•

6 Views

Evan D. Morris^1,2,3,4, Su Jin Kim^1,3, Jenna M. Sullivan^1,3,4, Shuo Wang^3,4, Marc D. Normandin⁵, Cristian C. Constantinescu⁶, Kelly P. Cosgrove^1,2,3

¹Diagnostic Radiology,Yale University, ²Psychiatry,Yale University, ³Yale PET Center,Yale University, ⁴Biomedical Engineering,Yale University, ⁵Nuclear Medicine,Massachusetts General Hospital, ⁶Radiological Sciences,University of California, Irvine

Summary

我们提出了一个新颖的PET成像的方法捕获由吸烟引起的多巴胺波动。在PET扫描仪的主题抽烟。动态PET图像的体素的体素的建模时间由LP-ntPET，其中包括一个随时间变化的多巴胺内。结果是'电影'在纹状体多巴胺波动的过程中吸烟。

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