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Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue
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Neuroscience
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JoVE Journal Neuroscience
Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue

Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue

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44,085 Views

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10:18 min

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October 29, 2012

DOI:

10.3791/50004-v

DOI:
10.3791/50004-v

•

10:18 min
October 29, 2012

•

13 Views
,
1Department of Molecular & Human Genetics,Baylor College of Medicine (BCM), 2Department of Neuroscience,Baylor College of Medicine (BCM), 3Jan and Dan Duncan Neurological Research Institute,Texas Children’s Hospital

Summary

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The development of optogenetics now provides the means to precisely stimulate genetically defined neurons and circuits, both in vitro and in vivo. Here we describe the assembly and implantation of a fiber optic for chronic photostimulation of brain tissue.

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OptogeneticsFiber-optic ImplantationChronic StimulationNeuronal ConnectivityElectrophysiologyCell-type SpecificIn VivoFiber Optic CouplerPhotostimulationNeuronal Circuits

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Cite this Article

Ung, K., Arenkiel, B. R. Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue. J. Vis. Exp. (68), e50004, doi:10.3791/50004 (2012).

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