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November 04, 2011
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Responding for food or drug-paired cues increases over the course of a period of abstinence and this may relate to an increased susceptibility to relapse behaviors. Here we detail a procedure for evaluating this "incubation of craving" in rats that have self-administered sucrose.
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Incubation Of Sucrose CravingRatsFood CravingFood-restricted DietKey Behavioral TransitionAbstinenceRelapseDrug CravingBehavioral And Neurobiological DeterminantsAddiction-like BehaviorsRat Model Of RelapseSelf-administering RatsConditioned Reinforcing PropertiesSucrose SeekingCue ReactivityLength Of Time Following Reward Self-administration
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Grimm, J. W., Barnes, J., North, K., Collins, S., Weber, R. A General Method for Evaluating Incubation of Sucrose Craving in Rats. J. Vis. Exp. (57), e3335, doi:10.3791/3335 (2011).
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