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November 21, 2011
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A surgical technique for implantation of commercially available telemetry transmitters used for continuous measurement of biopotential (one-lead ECG), heart rate, core body temperature and locomotor activity in freely moving mice is shown. Recommendations and protocols for post-operative care and pain relief, improving recovery, well being and survival rate are also presented.
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Radiotelemetry TransmittersECGHeart RateCore Body TemperatureActivityLaboratory MiceBiomedical ResearchAcademic SpherePharmaceutical IndustryCardiovascular ResearchPharmacological ResearchToxicological ResearchCirculatory SystemElectrocardiogramReliable ECG CurvesPhysiological DataConventional Measurement TechniquesRestrained AnimalTethered AnimalAnaesthetized AnimalRadiotelemetry Data CollectionConscious AnimalsUntethered Animals
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Cesarovic, N., Jirkof, P., Rettich, A., Arras, M. Implantation of Radiotelemetry Transmitters Yielding Data on ECG, Heart Rate, Core Body Temperature and Activity in Free-moving Laboratory Mice. J. Vis. Exp. (57), e3260, doi:10.3791/3260 (2011).
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