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口腔扁平上皮癌の同所性マウスモデルにおける腫瘍細胞の浸潤の多光子イメージング

JoVE Journal
Medicine

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JoVE Journal Medicine

Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma

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口腔扁平上皮癌の同所性マウスモデルにおける腫瘍細胞の浸潤の多光子イメージング

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12:03 min

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July 25, 2011

DOI:

DOI:

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12:03 min

July 25, 2011

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20 Views

Amanda Gatesman Ammer¹, Karen E. Hayes¹, Karen H. Martin¹, Lingqing Zhang², George A. Spirou³, Scott A. Weed¹

¹Department of Neurobiology and Anatomy, Program in Cancer Cell Biology,Mary Babb Randolph Cancer Center, West Virginia University, ²Sensory Neuroscience Research Center,West Virginia University , ³Departments of Otolaryngology and Physiology, Center for Neuroscience,West Virginia University

Summary

標識された細胞の多光子顕微鏡を通して舌内に口腔癌と腫瘍浸潤の定量的なモニタリングのマウスモデルの生成に関わる技術の包括的な概要が表示されます。このシステムは、抗浸潤化合物の分子の評価と薬効のための有用なプラットフォームとして機能することができます。

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