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Une stratégie pour identifier des mutations de novo dans les troubles courants comme l'autisme et la schizophrénie
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Medicine
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JoVE Journal Medicine
A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Une stratégie pour identifier des mutations de novo dans les troubles courants comme l'autisme et la schizophrénie

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25,414 Views

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05:51 min

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June 15, 2011

DOI:

10.3791/2534-v

DOI:
10.3791/2534-v

•

05:51 min
June 15, 2011

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25 Views
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1Centre of Excellence in Neuromics, CHUM Research Center and the Department of Medicine, Universite de Montreal, 2Center of Excellence in Neuromics, CHU Sainte Justine and CHUM Notre-Dame Research Centers, Universite de Montreal, 3Department of Medicine, Universite de Montreal

Summary

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Stratégie génétique moléculaire pour trouver des mutations de novo provoquant des troubles courants tels que l'autisme et la schizophrénie.

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De Novo MutationsCommon DisordersAutismSchizophreniaMutation RateLinkage Gene MappingAssociation StudiesMonozygotic TwinsDizygotic TwinsReproductive FitnessEnvironmental FactorsIncidence Rate

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Julie, G., Hamdan, F. F., Rouleau, G. A. A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia. J. Vis. Exp. (52), e2534, doi:10.3791/2534 (2011).

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