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Induction of Experimental Autoimmune Hypophysitis in SJL Mice
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Immunology and Infection
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JoVE Journal Immunology and Infection
Induction of Experimental Autoimmune Hypophysitis in SJL Mice

Induction of Experimental Autoimmune Hypophysitis in SJL Mice

DOI:
10.3791/2182-v

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10:38 min

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December 17, 2010

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, , ,
1Department of Pathology,The Johns Hopkins University

Chapters

  • 00:05Title
  • 00:59Introduction
  • 02:46Preparation
  • 04:46Collection of in vivo Experimental Outcomes: Blood Assays
  • 05:47Collection of post-mortem Experimental Outcomes: Pituitary Histopathology
  • 07:44Representative Histopathology
  • 09:13Conclusion

Summary

Automatic Translation

Automatic Translation

This video shows how to induce autoimmune hypophysitis in SJL mice and how to assess its severity by histopathology.

Tags

Experimental Autoimmune HypophysitisInductionSJL MiceAutoimmune DiseasesMouse ModelsPituitary ProteinsAdjuvantType 1A DiabetesNOD MouseAutoimmune ThyroiditisThyroglobulinMyasthenia GravisAcetylcholine ReceptorPathogenic AutoantigenCrude Pituitary Protein Preparation

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