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RNAi Screening for Host Factors Involved in Vaccinia Virus Infection using Drosophila Cells
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August 25, 2010
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Novel host factors involved in viral infection can be identified through cell-based genome-wide loss of function RNAi screening. A Drosophila cell culture model is particularly amenable to this approach due to the ease and efficiency of RNAi. Here we demonstrate this technique using vaccinia virus as an example.
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Moser, T. S., Sabin, L. R., Cherry, S. RNAi Screening for Host Factors Involved in Vaccinia Virus Infection using Drosophila Cells. J. Vis. Exp. (42), e2137, doi:10.3791/2137 (2010).
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