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Ejecución de la aplicación mAbscale para calcular las masas de terapias proteicas basadas en anticuerpos monoclonales
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03:04 min
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June 16, 2023
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Keyword Extraction:MAbscale ApplicationMonoclonal AntibodyProtein TherapeuticsHeavy ChainLight ChainBispecific AntibodiesTerminal CyclizationC Terminal ClippingChemical ModificationsLinkerPayloadAntibody Drug ConjugatesDisulfide BondsGlycosylationMass CalculationMass ErrorMonoclonal Antibody StandardN-linked GlycosylationBispecific Monoclonal AntibodyAntibody Drug Conjugate
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Harkins, T., Cao, L., Khatri, K. Running the mAbscale Application to Calculate the Masses of Monoclonal Antibody-Based Protein Therapeutics. J. Vis. Exp. (Pending Publication), e200341, doi:10.3791/200341 (2023).
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