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Author Spotlight: Integrating Organoid Models with Single-Cell and Spatial Transcriptomics Technologies
JoVE Journal
Gelişim Biyolojisi
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JoVE Journal Gelişim Biyolojisi
Generation and Downstream Analysis of Single-Cell and Single-Nuclei Transcriptomes in Brain Organoids

Author Spotlight: Integrating Organoid Models with Single-Cell and Spatial Transcriptomics Technologies

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02:19 min

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March 29, 2024

DOI:

10.3791/66225-v

DOI:
10.3791/66225-v

•

02:19 min
March 29, 2024

•

41 Views
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1Berlin Institute for Medical Systems Biology (BIMSB),Max Delbrück Center for Molecular Medicine (MDC), 2Institut für Biologie,Humboldt-Universität zu Berlin, 3Organoid platform, Berlin Institute for Medical Systems Biology (BIMSB),Max Delbrück Center for Molecular Medicine (MDC)

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Single-cell TranscriptomicsSingle-nucleus TranscriptomicsBrain OrganoidsCell Type IdentificationGene ExpressionCell LineageDevelopmental ProcessesMolecular Mechanisms

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Wandres, M., Aigner, D., Kastelic, N., Boltengagen, A., Rybak-Wolf, A., Rajewsky, N. Generation and Downstream Analysis of Single-Cell and Single-Nuclei Transcriptomes in Brain Organoids. J. Vis. Exp. (205), e66225, doi:10.3791/66225 (2024).

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