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A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
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October 13, 2023
DOI:
1Fizyoloji Bölümü,UCLA School of Medicine, 2Scalable Analytics Institute (ScAi) at Department of Computer Science,UCLA School of Engineering, 3NIH BRIDGE2AI Center at UCLA & NHLBI Integrated Cardiovascular Data Science Training Program,UCLA, 4Medical Informatics,University of California at Los Angeles (UCLA), 5Department of Medicine (Cardiology),UCLA School of Medicine
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A computational protocol, CaseOLAP LIFT, and a use case are presented for investigating mitochondrial proteins and their associations with cardiovascular disease as described in biomedical reports. This protocol can be easily adapted to study user-selected cellular components and diseases.
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Pelletier, A. R., Steinecke, D., Sigdel, D., Adam, I., Caufield, J. H., Guevara-Gonzalez, V., Ramirez, J., Verma, A., Bali, K., Downs, K., Wang, W., Bui, A., Ping, P. A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports. J. Vis. Exp. (200), e65084, doi:10.3791/65084 (2023).
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