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Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala
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JoVE Journal Nörobilim
Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala

Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala

2,136 Views

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09:49 min

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June 29, 2022

DOI:

10.3791/64113-v

DOI:
10.3791/64113-v

•

09:49 min
June 29, 2022

•

70 Views
, , , , , , , , ,
1Department of Neurosurgery,Xuanwu Hospital Capital Medical University, 2China Clinical Research Center for Epilepsy Capital Medical University, 3China Beijing Municipal Geriatric Medical Research Center

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The amygdala plays a key role in temporal lobe epilepsy, which originates in and propagates from this structure. This article provides a detailed description of the fabrication of deep brain electrodes with both recording and stimulating functions. It introduces a model of medial temporal lobe epilepsy originating from the amygdala.

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Cite this Article

Lu, Y., Dai, Y., Ou, S., Miao, Y., Wang, Y., Liu, Q., Wang, Y., Wei, P., Shan, Y., Zhao, G. Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala. J. Vis. Exp. (184), e64113, doi:10.3791/64113 (2022).

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