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Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording
JoVE Journal
Nörobilim
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JoVE Journal Nörobilim
Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording

Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording

DOI:

06:36 min

September 01, 2022

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Bölümler

  • 00:04Introduction
  • 01:13Preparation of an Optrode Array
  • 01:39Presurgical Preparation of Animal and Implantation Surgery
  • 03:45Setting Parameters and Conducting Optogenetic Stimulation, Electrophysiological Recording, and Data Analysis
  • 04:55Results: Electrophysiological Recording
  • 05:40Conclusion

Özet

Otomatik Çeviri

Here, we present the fabrication method of an optrode system with optical fibers for light delivery and an electrode array for neural recording. In vivo experiments with transgenic mice expressing channelrhodopsin-2 show the feasibility of the system for simultaneous optogenetic stimulation and electrophysiological recording.

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