A transient scald injury (65 °C ± 0.5 °C, 3 s) of one hind paw decreases the threshold (g) to von Frey filament stimulation of the ipsilateral side and alters gait pattern. Besides, burn injury induces depression-like behavior in the forced swimming test.
Choi, J., Kang, D., Kim, J., Lee, M., Choi, S., Park, J. B., Kim, H. Burn Injury-Induced Pain and Depression-Like Behavior in Mice. J. Vis. Exp. (175), e62817, doi:10.3791/62817 (2021).