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マウスにおける胎児の気管咬合モデル
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Gelişim Biyolojisi
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JoVE Journal Gelişim Biyolojisi
Transuterine Fetal Tracheal Occlusion Model in Mice
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マウスにおける胎児の気管咬合モデル

2,854 Views

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06:31 min

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February 05, 2021

DOI:

10.3791/61772-v

DOI:
10.3791/61772-v

•

06:31 min
February 05, 2021

•

3 Views
, , , , ,
1The Center for Fetal, Cellular & Molecular Therapy, Cincinnati Fetal Center, Division of Pediatric General and Thoracic Surgery,Cincinnati Children’s Hospital Medical Center, 2Department of Pediatric Surgery,Tekirdag Namik Kemal University School of Medicine, 3The Division of Critical Care Medicine, Department of Pediatrics,Cincinnati Children’s Hospital Medical Center

Özet

Automatically generated

先天性横隔膜ヘルニアおよび胎児気管閉塞の様々な動物モデルは、倫理的問題、コスト、外科的困難、大きさ、生存率、および遺伝的ツールの入手可能性に関する長所と短所を提示する。このモデルは気管閉塞および上昇した発光圧力が肺の発達に及ぼす影響を調べるための新しいツールを提供する。

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Cite this Article

Aydın, E., Joshi, R., Oria, M., Lim, F., Varisco, B. M., Peiro, J. L. Transuterine Fetal Tracheal Occlusion Model in Mice. J. Vis. Exp. (168), e61772, doi:10.3791/61772 (2021).

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