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Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice
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JoVE Journal Davranış
Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice

Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice

DOI:
10.3791/61548-v

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09:37 min

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August 13, 2020

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, ,
1Department of Psychology, Behavioral and Systems Neuroscience Area,The State University of New Jersey, 2Graduate Program in Neuroscience,Rutgers, The State University of New Jersey

Bölümler

  • 00:04Introduction
  • 00:50Chronic Corticosterone (CORT)
  • 01:52Y-Maze Apparatus Habituation
  • 02:30Y-Maze Forced-Choice Training
  • 03:13Y-Maze Free Choice Training
  • 03:51Y-Maze Barrier Testing
  • 04:51Chronic Non-Discriminatory Social Defeat Stress (CNSDS)
  • 06:51Results: Representative Chronic Stress-Induced Effort-Related Choice Behavior Analyses
  • 08:55Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

The Y-maze barrier task is a behavior test that examines motivation to expend effort for reward. Here, we discuss testing multiple well-validated chronic stressors including chronic corticosterone and social defeat stress with this behavior, as well as the novel chronic non-discriminatory social defeat stress (CNSDS), which is effective in females.

Etiketler

Chronic StressEffort-related ChoiceY-mazeBarrier TaskMiceReward BehaviorMood DisordersBeta-cyclodextrinCorticosteroneFood DeprivationForced ChoiceFree Choice

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