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Fear Incubation Using an Extended Fear-Conditioning Protocol for Rats
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August 22, 2020
DOI:
1School of Psychology,Universidad Pedagógica y Tecnológica de Colombia, 2Animal Behavior Laboratory,Fundación Universitaria Konrad Lorenz, 3Psikoloji Bölümü,Universidad de Los Andes, 4School of Veterinary Medicine, Animal Health Department,Universidad Nacional de Colombia, 5Psikoloji Bölümü,Troy University, 6Department of Neurobiology,University of Alabama at Birmingham
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We describe an extended fear-conditioning protocol that produces overtraining and fear incubation in rats. This protocol entails a single training session with 25 tone-shock pairings (i.e., overtraining) and a comparison of conditioned freezing responses during context and cue tests 48 h (short-term) and 6 weeks (long-term) after training.
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Acevedo-Triana, C., Rico, J. L., Ortega, L. A., Cardenas, M. A. N., Cardenas, F. P., Rojas, M. J., Forigua-Vargas, J. C., Cifuentes, J., Hurtado-Parrado, C. Fear Incubation Using an Extended Fear-Conditioning Protocol for Rats. J. Vis. Exp. (162), e60537, doi:10.3791/60537 (2020).
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