Described here is a novel automated experimental system that offers an alternative to the three-chamber test and also solves several caveats. This system supplies multiple behavioral parameters that enable rigorous analysis of small rodent behavioral dynamics during the social preference and social novelty preference tests.
Netser, S., Haskal, S., Magalnik, H., Bizer, A., Wagner, S. A System for Tracking the Dynamics of Social Preference Behavior in Small Rodents. J. Vis. Exp. (153), e60336, doi:10.3791/60336 (2019).