Described here are three experimental approaches for studying the dynamics of HIV infection in humanized mice. The first permits the study of chronic infection events, whereas the two latter allows for the study of acute events after primary infection or viral reactivation.
Perdomo-Celis, F., Medina-Moreno, S., Heredia, A., Davis, H., Bryant, J., Zapata, J. C. Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models. J. Vis. Exp. (154), e60315, doi:10.3791/60315 (2019).