Dergi
/
Tıp
/
Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits
JoVE Journal
Tıp
This content is Free Access.
JoVE Journal Tıp
Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

9,537 Views

•

07:43 min

•

January 08, 2020

DOI:

10.3791/60126-v

DOI:
10.3791/60126-v

•

07:43 min
January 08, 2020

•

3 Views
, , ,
1Department of Ophthalmology,Stony Brook University, 2Tıp Fakültesi,Stony Brook University, 3Medicon Pharmaceuticals, Inc, 4Department of Preventive Medicine,Stony Brook University

Özet

Automatically generated

A novel approach is presented to induce chronic dry eye disease in rabbits by surgically removing all orbital lacrimal glands. This method, distinct from those previously reported, produces a stable, reproducible model of aqueous deficient dry eye well suited to study tear physiology and pathophysiology and ocular therapeutics.

Explore More Videos

Severe Dry EyeDacryoadenectomyRabbit ModelAqueous Deficient Dry EyeLacrimal Gland RemovalNictitating MembraneOrbital Superior Lacrimal GlandSurgical TechniqueSurgical AnatomyOphthalmology Research

Read Article

Cite this Article

Honkanen, R. A., Huang, L., Huang, W., Rigas, B. Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits. J. Vis. Exp. (155), e60126, doi:10.3791/60126 (2020).

Download .ris file

Copy

Share Video

.

Copy