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Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits
JoVE 杂志
医学
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JoVE 杂志 医学
Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

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07:43 min

January 08, 2020

DOI:

07:43 min
January 08, 2020

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Summary

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A novel approach is presented to induce chronic dry eye disease in rabbits by surgically removing all orbital lacrimal glands. This method, distinct from those previously reported, produces a stable, reproducible model of aqueous deficient dry eye well suited to study tear physiology and pathophysiology and ocular therapeutics.

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