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Quantification of Atherosclerosis in Mice
Bölümler
- 00:04Başlık
- 00:56Murine Aorta Microdissection
- 01:57En Face Aortic Arch and Brachiocephalic Artery Analysis
- 04:20Aortic Root Cryosectioning
- 05:29Results: Representative Atherosclerotic Lesion Analyses
- 06:31Conclusion
Murine models of atherosclerosis are useful tools to investigate pathogenic pathways on a molecular level, but require standardized quantification of lesion development. This protocol describes an optimized method to determine lesion size in the major arterial vessels including the aortic root, aortic arch, and brachiocephalic artery.
