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Swimming Induced Paralysis to Assess Dopamine Signaling in Caenorhabditis elegans
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April 03, 2019
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1Harriet Wilkes Honors College,Florida Atlantic University, John D MacArthur Campus, 2Integrative Biology and Neuroscience program, College of Science,Florida Atlantic University, 3Brain Institute,Florida Atlantic University, 4Department of Biomedical Science, Charles E. Schmidt College of Medicine,Florida Atlantic University
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Swimming induced paralysis (SWIP) is a well-established behavioral assay used to study the underlying mechanisms of dopamine signaling in Caenorhabditis elegans (C. elegans). However, a detailed method to perform the assay is lacking. Here, we describe a step-by-step protocol for SWIP.
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Kudumala, S., Sossi, S., Carvelli, L. Swimming Induced Paralysis to Assess Dopamine Signaling in Caenorhabditis elegans. J. Vis. Exp. (146), e59243, doi:10.3791/59243 (2019).
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