Structured protocols are necessary to provide answers on research questions in critically ill patients. The Simple Intensive Care Studies (SICS) provides an infrastructure for repeated measurements in critically ill patients including clinical examination, biochemical analysis and ultrasonography. SICS projects have specific focus but the structure is flexible to other investigations.
Wiersema, R., Castela Forte, J. N., Kaufmann, T., de Haas, R. J., Koster, G., Hummel, Y. M., Koeze, J., Franssen, C. F. M., Vos, M. E., Hiemstra, B., Keus, F., van der Horst, I. C. Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies. J. Vis. Exp. (143), e58802, doi:10.3791/58802 (2019).