Here we present a protocol to investigate the effect of the nullification of gustation-related genes on immune responses in a dextran sulfate sodium (DSS)-induced inflammatory bowel disease (IBD) mouse model.
Du, Y., Liu, Q., Luo, X., Zhao, D., Xue, J., Feng, P., Margolskee, R. F., Wang, H., Huang, L. Effects of Taste Signaling Protein Abolishment on Gut Inflammation in an Inflammatory Bowel Disease Mouse Model. J. Vis. Exp. (141), e58668, doi:10.3791/58668 (2018).