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時空ゲスト活性型タグとしてケージの分子接着剤を用いた生細胞内の核内移行を制御
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Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags
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時空ゲスト活性型タグとしてケージの分子接着剤を用いた生細胞内の核内移行を制御

10,055 Views

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10:10 min

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January 17, 2019

DOI:

10.3791/58631-v

DOI:
10.3791/58631-v

•

10:10 min
January 17, 2019

•

9 Views
, , ,
1Department of Chemistry and Biotechnology, School of Engineering,University of Tokyo, 2Riken Center for Emergent Matter Science

Özet

Automatically generated

このプロトコルでは、ケージ分子接着剤タグを使用して生きている細胞での核内移行を光トリガーについて説明します。このメソッドは、サイト選択的核ターゲット ドラッグデリバリーの有望です。

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Cite this Article

Mogaki, R., Okuro, K., Arisaka, A., Aida, T. Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags. J. Vis. Exp. (143), e58631, doi:10.3791/58631 (2019).

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