Here, we present a protocol to detect discrete metal oxygen clusters, polyoxometalates (POMs), at the single molecule limit using a biological nanopore-based electronic platform. The method provides a complementary approach to traditional analytical chemistry tools used in the study of these molecules.
Ettedgui, J., Forstater, J., Robertson, J. W., Kasianowicz, J. J. High Resolution Physical Characterization of Single Metallic Nanoparticles. J. Vis. Exp. (148), e58257, doi:10.3791/58257 (2019).