A protocol for enhancing carbohydrate ion signals in MALDI mass spectrometry by reforming crystalline structures during sample preparation processes is demonstrated.
Ou, Y., Kuo, S., Lee, H., Chang, H., Wang, Y. An Efficient Sample Preparation Method to Enhance Carbohydrate Ion Signals in Matrix-assisted Laser Desorption/Ionization Mass Spectrometry. J. Vis. Exp. (137), e57660, doi:10.3791/57660 (2018).