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Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
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Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
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July 01, 2018
DOI:
1College of Veterinary Medicine,Nanjing Agricultural University, 2Key Lab of Animal Bacteriology,Ministry of Agriculture, 3OIE Reference Lab for Swine Streptococcosis, 4School of Medicine,Tsinghua University, 5Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses
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Here, we describe the intracranial subarachnoidal route of infection in mice to study roles of biofilms in Streptococcus suis meningitis. This infection model is also suitable for studying the pathogenesis of other bacterial meningitis and the efficacy of new drugs against bacterial meningitis.
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Zhang, S., Gao, X., Xiao, G., Lu, C., Yao, H., Fan, H., Wu, Z. Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model. J. Vis. Exp. (137), e57658, doi:10.3791/57658 (2018).
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