Bu içeriği görüntülemek için JoVE aboneliği gereklidir. Oturum açın veya ücretsiz deneme sürümünü başlatın.
Un enzima Split-TET2 ingegnerizzati per chimica-inducible DNA Hydroxymethylation e rimodellamento epigenetico
6,481 Views
•
08:34 min
•
December 18, 2017
DOI:
1Centre for Epigenetics and Disease Prevention, Department of Molecular and Cellular Medicine, Institute of Biosciences and Technology, College of Medicine,Texas A&M University, 2Centre for Translational Cancer Research, Department of Medical Physiology, Institute of Biosciences and Technology, College of Medicine,Texas A&M University
Özet
Automatically generated
Protocolli dettagliati per l'introduzione di un enzima derivati dal Spalato-TET2 (sidro) nelle cellule di mammiferi per chimica viscoelastica DNA hydroxymethylation e rimodellamento epigenetici sono presentati.
Read Article
Cite this Article
Lee, M., Zhou, Y., Huang, Y. An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling. J. Vis. Exp. (130), e56858, doi:10.3791/56858 (2017).
Copy