Dergi
/
Nörobilim
/
מדידה כמותית של חלבונים וγ Secretase-בתיווך קודמן עמילואיד, המחשוף דרגה ב מבוססת תא לוציפראז כתב Assay פלטפורמות
JoVE Journal
Nörobilim
Bu içeriği görüntülemek için JoVE aboneliği gereklidir.  Oturum açın veya ücretsiz deneme sürümünü başlatın.
JoVE Journal Nörobilim
Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms
Please note that all translations are automatically generated. Click here for the English version.

מדידה כמותית של חלבונים וγ Secretase-בתיווך קודמן עמילואיד, המחשוף דרגה ב מבוססת תא לוציפראז כתב Assay פלטפורמות

6,650 Views

•

06:40 min

•

January 25, 2018

DOI:

10.3791/56795-v

DOI:
10.3791/56795-v

•

06:40 min
January 25, 2018

•

2 Views
, , , , , ,
1Laboratory of Molecular Neurobiology, Institute of Cellular and Organismic Biology,Academia Sinica

Etiketler

Gamma-secretaseAmyloid Precursor ProteinNotch CleavageCell-based Luciferase Reporter AssayAlzheimer’s DiseaseGamma-secretase ModulatorsSubstrate SelectivityNeuroblastomaNG CellsCG CellsTetracyclineDMSOCL-387785DAPTErbB1/ErbB2 InhibitorsLuciferase AssayLuminescence Microplate Reader

Read Article

Cite this Article

Wang, B., Wu, P., Chen, Y., Chang, Y., Bhore, N., Wu, P., Liao, Y. Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms. J. Vis. Exp. (131), e56795, doi:10.3791/56795 (2018).

Download .ris file

Copy

Share Video

.

Copy