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Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays
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Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays

Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays

9,470 Views

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10:45 min

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May 29, 2017

DOI:

10.3791/55726-v

DOI:
10.3791/55726-v

•

10:45 min
May 29, 2017

•

15 Views
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1Krasnow Institute for Advanced Study,George Mason University, 2Neural Engineering, Bioengineering,George Mason University, 3Neural Engineering, Computer Science,George Mason University, 4Electrical and Computer Engineering,George Mason University

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Mouse neuronal cells cultured on multi-electrode arrays display an increase in response following electrical stimulation. This protocol demonstrates how to culture neurons, how to record activity, and how to establish a protocol to train the networks to respond to patterns of stimulation.

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Gertz, M. L., Baker, Z., Jose, S., Peixoto, N. Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays. J. Vis. Exp. (123), e55726, doi:10.3791/55726 (2017).

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