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Massaspectrometrie en luminogene gebaseerde benaderingen voor karakteriseren Fase I Metabolic competentie van<em> In Vitro</em> Cell Cultures
JoVE Journal
Biyokimya
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JoVE Journal Biyokimya
Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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Massaspectrometrie en luminogene gebaseerde benaderingen voor karakteriseren Fase I Metabolic competentie van<em> In Vitro</em> Cell Cultures

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10:44 min

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March 28, 2017

DOI:

10.3791/55502-v

DOI:
10.3791/55502-v

•

10:44 min
March 28, 2017

•

1 Views
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1Research and Development,British American Tobacco

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Metabole competentie van in vitro systemen is een belangrijke voorwaarde voor de biotransformatie en dispositie van drugs en toxische stoffen. In dit protocol beschrijven we de toepassing van referentie- metabole probes fase I metabolisme in celkweken beoordelen.

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Baxter, A., Minet, E. Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures. J. Vis. Exp. (121), e55502, doi:10.3791/55502 (2017).

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