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Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
JoVE 杂志
生物化学
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JoVE 杂志 生物化学
Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures

9,484 Views

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10:44 min

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March 28, 2017

DOI:

10.3791/55502-v

DOI:
10.3791/55502-v

•

10:44 min
March 28, 2017

•

9 Views
,
1Research and Development,British American Tobacco

Tags

Mass SpectrometryLuminogenicPhase I MetabolismIn Vitro Cell CulturesCytochrome P450CYP EnzymesProbe SubstratesInhibitorsHepatic Cell LineWilliams’ E MediumAir-liquid InterfaceTransepithelial ResistanceCilia Beat Frequency

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Baxter, A., Minet, E. Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures. J. Vis. Exp. (121), e55502, doi:10.3791/55502 (2017).

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