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Uso de un Modelo de Cochinillo para el Estudio de la Neurotoxicidad de Desarrollo inducida por Anestesia (AIDN): Un Enfoque de Neurociencia Translacional
1Department of Anesthesiology,Ohio State University College of Medicine, 2Department of Anesthesiology and Pain Medicine,Nationwide Children’s Hospital, 3Department of Anaesthesia and Critical Care Medicine,University of Toronto, 4Department of Biomedical Sciences, Section of Anatomic Pathology,Cornell University College of Veterinary Medicine, 5Department of Pathology and Anatomy,Ohio State University College of Medicine, 6Department of Pathology and Laboratory Medicine,Nationwide Children’s Hospital
Bölümler
- 00:05Başlık
- 00:45Preparing the Animal
- 02:49Femoral Artery Catheterization
- 04:11Collecting Data and Completing Surgery
- 05:30Results: Consistency and Reproducibility of Lab Values
- 06:07Conclusion
La investigación sobre la neurotoxicidad del desarrollo inducida por la anestesia (AIDN) se ha centrado en los roedores, que no son ampliamente aplicables a los seres humanos. Los modelos de primates no humanos son más relevantes, pero son costo prohibitivos y difíciles de usar para la experimentación. El lechón, por el contrario, es un modelo animal clínicamente relevante y práctico, ideal para el estudio de la neurotoxicidad anestésica.
Etiketler
Piglet ModelAnesthetic-induced Developmental Neurotoxicity (AIDN)Translational NeurosciencePhysiologic HomeostasisAnesthesia InductionPulse OximetryBlood PressureElectrocardiographyTemperatureTracheal IntubationLidocaineEnd-tidal Carbon DioxideOphthalmic OintmentAntibioticSterile FieldFemoral Neurovascular Bundle
