Bu içeriği görüntülemek için JoVE aboneliği gereklidir. Oturum açın veya ücretsiz deneme sürümünü başlatın.
Lateral Chronic Cranial Window Preparation Enables In Vivo Observation Following Distal Middle Cerebral Artery Occlusion in Mice
Bölümler
- 00:05Başlık
- 00:43Lateral Chronic Cranial Window Preparation
- 03:40Intravital Microscopy
- 04:20Distal Middle Cerebral Artery Occlusion (MCAo)
- 07:04Results: Lateral Chronic Cranial Window with Distal MCAo
- 08:02Conclusion
Surgical occlusion of a distal middle cerebral artery branch (MCAo) is a frequently used model in experimental stroke research. This manuscript describes the basic technique of permanent MCAo, combined with the insertion of a lateral cranial window, which offers the opportunity for longitudinal intravital microscopy in mice.
