A procedure for the isolation of EOB-DTPA and subsequent complexation with natural Ga(III) and 68Ga is presented herein, as well as a thorough analysis of all compounds and investigations on labeling efficiency, in vitro stability and the n-octanol/water distribution coefficient of the radiolabeled complex.
Greiser, J., Niksch, T., Weigand, W., Freesmeyer, M. Investigations on the Ga(III) Complex of EOB-DTPA and Its 68Ga Radiolabeled Analogue. J. Vis. Exp. (114), e54334, doi:10.3791/54334 (2016).