A method for investigating the structure of a protein photoreceptor using atomic force microscopy (AFM) is described in this paper. PeakForce Quantitative Nanomechanical Property Mapping (PF-QNM) reveals intact protein dimers on a mica surface.
Kroeger, M. E., Sorenson, B. A., Thomas, J. S., Stojković, E. A., Tsonchev, S., Nicholson, K. T. Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping. J. Vis. Exp. (92), e52164, doi:10.3791/52164 (2014).