Dergi
/
Nörobilim
/
Regie dopaminergen Neuron Differenzierung von humanen pluripotenten Stammzellen
JoVE Journal
Nörobilim
Bu içeriği görüntülemek için JoVE aboneliği gereklidir.  Oturum açın veya ücretsiz deneme sürümünü başlatın.
JoVE Journal Nörobilim
Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells
Please note that all translations are automatically generated. Click here for the English version.

Regie dopaminergen Neuron Differenzierung von humanen pluripotenten Stammzellen

16,196 Views

•

06:40 min

•

September 15, 2014

DOI:

10.3791/51737-v

DOI:
10.3791/51737-v

•

06:40 min
September 15, 2014

•

13 Views
, ,
1Institute for Stem Cell Biology and Regenerative Medicine,Stanford University School of Medicine, 2Department of Obstetrics and Gynecology,Stanford University School of Medicine

Özet

Automatically generated

We, based on knowledge from developmental biology and published research, developed an optimized protocol to efficiently generate A9 midbrain dopaminergic neurons from both human embryonic stem cells and human induced pluripotent stem cells, which would be useful for disease modeling and cell replacement therapy for Parkinson’s disease.

Explore More Videos

Dopaminergic NeuronsPluripotent Stem CellsParkinson’s DiseaseCell Replacement TherapyFloor PlateVentral MidlineNeural DevelopmentDifferentiationHuman Embryonic Stem CellsHuman Induced Pluripotent Stem CellsIn Vitro Disease ModelingDrug ScreeningCell Transplantation

Read Article

Cite this Article

Zhang, P., Xia, N., Reijo Pera, R. A. Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells. J. Vis. Exp. (91), e51737, doi:10.3791/51737 (2014).

Download .ris file

Copy

Share Video

.

Copy