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トランスジェニック齧歯類アッセイ男性生殖細胞変異頻度を定量化するための
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August 06, 2014
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De novo mutations in the male germline may contribute to adverse health outcomes in subsequent generations. Here we describe a protocol for the use of a transgenic rodent model for quantifying mutations in male germ cells induced by environmental agents.
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O'Brien, J. M., Beal, M. A., Gingerich, J. D., Soper, L., Douglas, G. R., Yauk, C. L., Marchetti, F. Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency. J. Vis. Exp. (90), e51576, doi:10.3791/51576 (2014).
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