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Medição de fronto-límbico Atividade Usando um emocional Oddball Task em Crianças com Familial alto risco para Esquizofrenia
JoVE Journal
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JoVE Journal Davranış
Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Medição de fronto-límbico Atividade Usando um emocional Oddball Task em Crianças com Familial alto risco para Esquizofrenia

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13:08 min

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December 02, 2015

DOI:

10.3791/51484-v

DOI:
10.3791/51484-v

•

13:08 min
December 02, 2015

•

5 Views
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1Psikiyatri Bölümü,University of North Carolina at Chapel Hill School of Medicine, 2Duke-UNC Brain Imaging and Analysis Center,Duke University Medical Center, 3Curriculum in Neurobiology,University of North Carolina at Chapel Hill

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This paper describes how to use the emotional oddball task and fMRI to measure brain activation in children and adolescents at familial high risk for schizophrenia (FHR). FMRI was used to measure differences in fronto-striato-limbic regions during an emotional oddball task. Children with FHR exhibited abnormal functional activation during adolescence.

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FMRIEmotional Oddball TaskFamilial High RiskSchizophreniaFrontal-limbic ActivityAdolescenceCognitive ChangesExecutive ProcessingEmotion Processing

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Hart, S. J., Shaffer, J. J., Bizzell, J., Weber, M., McMahon, M. A., Gu, H., Perkins, D. O., Belger, A. Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia. J. Vis. Exp. (106), e51484, doi:10.3791/51484 (2015).

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