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Glasvezel-implantatie voor chronische Optogenetic Stimulatie van hersenweefsel
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JoVE Journal Nörobilim
Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue
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Glasvezel-implantatie voor chronische Optogenetic Stimulatie van hersenweefsel

44,024 Views

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10:18 min

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October 29, 2012

DOI:

10.3791/50004-v

DOI:
10.3791/50004-v

•

10:18 min
October 29, 2012

•

13 Views
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1Department of Molecular & Human Genetics,Baylor College of Medicine (BCM), 2Nörobilim Bölümü,Baylor College of Medicine (BCM), 3Jan and Dan Duncan Neurological Research Institute,Texas Children’s Hospital

Özet

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De ontwikkeling van optogenetics biedt nu de middelen om nauwkeurig te stimuleren genetische gedefinieerde neuronen en circuits,<em> In vitro</em> En<em> In vivo</em>. Hier beschrijven we de montage en implantatie van een glasvezel voor chronische fotostimulering van hersenweefsel.

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OptogeneticsFiber-optic ImplantationChronic StimulationNeuronal ConnectivityElektrofizyolojiCell-type SpecificIn VivoFiber Optic CouplerPhotostimulationNeuronal Circuits

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Ung, K., Arenkiel, B. R. Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue. J. Vis. Exp. (68), e50004, doi:10.3791/50004 (2012).

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