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An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells
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An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells
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August 15, 2012
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We have developed an in vitro malaria-HIV-1 co-infection model to study the impact of Plasmodium falciparum on the HIV-1 replicative cycle in human primary monocyte-derived macrophages. This versatile system can easily be adapted to other primary cell types susceptible to HIV-1 infection.
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In Vitro Co-infection ModelPlasmodium FalciparumHIV-1 InteractionsHuman Primary Monocyte-derived Immune CellsMalariaHIV-1Co-infectionsDisease ProgressionTransmissionImmunological MechanismsSoluble Malarial AntigensHIV-1 InfectionReactivationImmune CellsP. Falciparum Schizont Stage ParasitesPeripheral Blood Mononuclear Cells
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Andreani, G., Gagnon, D., Lodge, R., Tremblay, M. J., Richard, D. An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells. J. Vis. Exp. (66), e4166, doi:10.3791/4166 (2012).
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