Noroviruses are a major cause of gastroenteritis yet molecular techniques for their characterisation are still relatively new. Here we report two different reverse genetics approaches for the efficient recovery of murine norovirus (MNV), the only member of this genus which can be propagated in cell culture.
Arias, A., Ureña, L., Thorne, L., Yunus, M. A., Goodfellow, I. Reverse Genetics Mediated Recovery of Infectious Murine Norovirus. J. Vis. Exp. (64), e4145, doi:10.3791/4145 (2012).