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Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice
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June 13, 2012
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This article describes an optimized sequence of events for multimodal imaging of cellular grafts in rodent brain using: (i) in vivo bioluminescence and magnetic resonance imaging, and (ii) post mortem histological analysis. Combining these imaging modalities on a single animal allows cellular graft evaluation with high resolution, sensitivity and specificity.
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De Vocht, N., Reekmans, K., Bergwerf, I., Praet, J., Hoornaert, C., Le Blon, D., Daans, J., Berneman, Z., Van der Linden, A., Ponsaerts, P. Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice. J. Vis. Exp. (64), e3906, doi:10.3791/3906 (2012).
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