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Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure
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Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure

Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure

DOI:
10.3791/3704-v

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10:07 min

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March 20, 2012

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,
1Program in Developmental Biology,Children’s Memorial Research Center, 2Pediatri Anabilim Dalı,Northwestern University

Bölümler

  • 00:05Başlık
  • 01:25Treatment of Embryos with Ethanol and Collection
  • 03:36Assessing Ethanol-induced Gene Expression Changes and Developmental Consequences
  • 05:40Manipulating the Zebrafish Embryo
  • 06:49Representative Zebrafish Ethanol-exposure Results
  • 09:40Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

In order to understand the molecular mechanisms of the ethanol-induced developmental damage, we have developed a zebrafish model of ethanol exposure and are exploring the physical, cellular, and genetic alterations that occur after ethanol exposure1. We then seek to find potential interventions and rapidly test them in this animal model.

Etiketler

Teratogenic ChangesZebrafish ModelFetal Alcohol ExposureFetal Alcohol Syndrome (FAS)Fetal Alcohol Spectrum Disorder (FASD)Maternal Alcohol ConsumptionDevelopmental Ethanol ExposureZebrafish EmbryoTeratogen StudyGross Developmental DefectsZebrafish FAS Model

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