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Rodent Stereotaxic Surgery and Animal Welfare Outcome Improvements for Behavioral Neuroscience
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07:01 min
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January 30, 2012
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Stereotaxic surgery on rodents allows for targeted administration of drugs or electrical stimulation and recordings in awake, behaving animals. In this video presentation we will demonstrate recent procedural refinements to this long-standing procedure that successfully improved survival rate and reduced post-surgical weight loss.
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Rodent Stereotaxic SurgeryAnimal WelfareBehavioral NeuroscienceCannulae ImplantationBrain RegionsNeurotransmitter ManipulationSignaling PathwaysAwake Behaving AnimalsElectrode ImplantationElectrophysiological StimulationNeuroplasticityBrain NetworksSurgical Techniques In RodentsOxygen SupplementationBlood Oxygenation MonitoringHeart Rate MonitoringPost-surgical CareSurvival Rate ImprovementWeight Loss ReductionActive Animal Post-surgery
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Fornari, R. V., Wichmann, R., Atsak, P., Atucha, E., Barsegyan, A., Beldjoud, H., Messanvi, F., Thuring, C. M., Roozendaal, B. Rodent Stereotaxic Surgery and Animal Welfare Outcome Improvements for Behavioral Neuroscience. J. Vis. Exp. (59), e3528, doi:10.3791/3528 (2012).
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